Our Skin Science
2011 Taiwan ITRI team first conducted the research and development on MMpH+ encapsulation materials.
2013 After conducting the market research and the evaluation on MMpH+, they decided to tap into the domain of skin care.
2014 Research team put active ingredient MMpH+ into human skin reaction test.
2015 IRB human skin test proved that the active ingredient MMpH+ has profound effects in easing collagen loss of the dermis and stimulating collagen generation.
2016 The team launched Enzyme Secret Anti-Aging Serum, the 1st anti-aging product with active ingredient MMpH+.
2017 Combine MMpH+ to develop new anti-photoaging formula
2018 Launced the new Enzyme Secret AP-I anti-aging serum
2018 Developed AMELIORAGE serum (same as human test formula) & AMELIORAGE upgraded cream formula
2018 AMELIORAGE Regenerating Cream has been tested on human efficacy & consumer in well-kown French laboratories
2019 The full range of AMELIORAGE products have obtained EU regulations and related certifications, and can be freeely sold in the 27 EU countries and UK.
2019 Launched the global brand AMELIORAGE series
The biocompatible natural polymer, MMpH+, was originally developed in the unique anti-cancer drug capusul material research of the Industrial Technology Research Institute. DFON research team conducted a skin reaction test and found that MMpH+ has the effect of delaying skin aging.
Dynamic Balance of collagen
Most anti-aging products only focus on how to regenerate collagen, but neglect the rate of loss is also the key to effectively achieve collagen regeneration. After three years of rigorous human testing and market evaluation, DFON R&D team has achieved the result of “delaying loss, natural generation”. We successfully launch Enzyme Secret and AMELIORAGE series containing MMpH+ patented anti-aging active ingredients.
Uphold Scientific spirit, be realistic and innovative
DFON has never stopped pursuing innovation. In 2017, the R&D team combined with MMpH+ to launch an anti-photoaging formula, and in 2018, we developed an upgraded formula of AMELIORAGE regenerating Elixir and cream. While pursuing excellence, DFON firmly believes that quality is the cornerstone of the long-term development of the brand. Therefore, we conduct efficacy and safety testing of each product. In 2019, the full range of AMELIORAGE products had obtained the most stringent EU safety certification of PIF (Product Information File), CPSR (Cosmetic Product Safrty Report) and (Cosmetic Products Notification Portal).
Non cytotoxicity test
ISO 10993 In vitro Agar Diffusion Test (by ITRI MCL Lab), GLP and TAF Lab (by MEDGAEA)
• The hospital IRB committee approved: Skin Irritation by Single-Application Patch Test
• US AMA Lab perform skin safety testing for different race.
• In vitro skin irritation test：OECD 439 In vitro skin irritation test , by ITRI BDL Lab
• The hospital IRB committee approved: efficacy test of epidermal water content, skin elasticity, skin firmness, skin wrinkles, skin pores, dermis collagen intensity.
• French iEC laboratory conducts human efficacy tests to test skin water content before and after 30 min & 28 days.
• French SYRES laboratory conducts human tests on consumer efficacy, skin sensoriality, acceptability and tolerance.
• In vitro test: MMP enzyme balance, collagen regenration, by DFON science and ITRI MCL Lab.
Efficacy is tested by professional equipments
Skin structure test: dermis and subcutaneous collagen scanning probe, mainly to observe skin keratin thickness and collagen intensity of dermis and subcutaneous.
Cutometer® | Tewameter® | Corneometer®
Skin condition assessment: assess skin elasticity measurements, Transepidermal Water Loss(TEWL), hydration level of skin surface(stratum corneum).
Skin Topography: a unique UVA-ligh video camera with high resolution to study the skin surface directly.
Multifunctional skin detector: analyze the skin condition of the whole face by taking pictures, including: wrinkles, pores, superficial spots, and deep spots.